Journal Publications

  1. Biofabrication of Thick Vascularized Neo-Pedicle Flaps for Reconstructive Surgery.
    Stephens, C., Spector, J.A., Butcher, J.T. 
    Translational Medicine. 2019 Sep;211:84-122. doi: 10.1016/j.trsl.2019.05.003. Epub 2019 May 21. Review. PMID: 31170376.

  2. Calpain 9 as a Novel Therapeutic Target in TGFb-Induced Mesenchymal Transition and Fibrosis.
    David H. Kim, James D. Beckett, Varun Nagpal, Manuel A. Seman-Senderos, Russell A. Gould, Tyler J. Creamer, Elena Gallo MacFarlane, Yichun Chen, Djahida Bedja, Jonathan T. Butcher, Wayne Mitzner, Rosanne Rouf, Shoji Hata, Daniel S. Warren, Harry C. Dietz.
    Science Translational Medicine. 2019 Jul 17;11(501). pii: eaau2814. doi: 10.1126/scitranslmed.aau2814. PMID: 31316008.

  3. Spatial regulation of valve interstitial cell phenotypes within three-dimensional micropatterned hydrogels.
    Duan, B., Xu, C., Das, S., Chen, J.M., and Butcher, J.T.
    ACS Biomaterials Science and Engineering. 2019 [In press].

  4. Systematic analysis of the smooth muscle wall phenotype of the pharyngeal arch arteries during their reorganization into the great vessels and its association with hemodynamics.
    Ryvlin, J.*, Lindsey, S.E.*, and Butcher, J.T.
    Anatomical Record. s;302(1):153-162. doi: 10.1002/ar.23942. Epub 2018 Nov 9.
    *These authors contributed equally to this work. PMID: 30312026 PMCID: PMC6312499.

  5. ROBO4 variants predispose individuals to bicuspid aortic valve and thoracic aortic aneurysm.
    Gould RA, Aziz H, Woods CE, Seman-Senderos MA, Sparks E, Preuss C, Wünnemann F, Bedja D, Moats CR, McClymont SA, Rose R, Sobreira N, Ling H, MacCarrick G, Kumar AA, Luyckx I, Cannaerts E, Verstraeten A, Björk HM, Lehsau AC, Jaskula-Ranga V, Lauridsen H, Shah AA, Bennett CL, Ellinor PT, Lin H, Isselbacher EM, Lino Cardenas CL, Butcher JT, Hughes GC, Lindsay ME; Baylor-Hopkins Center for Mendelian Genomics; MIBAVA Leducq Consortium, Mertens L, Franco-Cereceda A, Verhagen JMA, Wessels M, Mohamed SA, Eriksson P, Mital S, Van Laer L, Loeys BL, Andelfinger G, McCallion AS, Dietz HC.
    Nat Genet. 2019 Jan;51(1):42-50. doi: 10.1038/s41588-018-0265-y. Epub 2018 Nov 19. PMID: 30455415 PMCID: PMC6309588.

  6. Cardiac regeneration following cryoinjury in the adult zebrafish targets a maturation-specific biomechanical remodeling program.
    Yu, J.K., Sarathchandra, P., Chester, A., Yacoub, M., Brand, T., and Butcher, J.T. 
    Scientific Reports 2018 Oct 23;8(1):15661. doi: 10.1038/s41598-018-33994-8. PMID: 30353076. PMCID: PMC6199254

  7. Cohort-based multiscale analysis of hemodynamic-driven growth and remodeling of the embryonic pharyngeal arch.
    Lindsey, S., Butcher, JT*, and Vingon-Clementel, I*.
    Development 2018 Oct 17;145(20). pii: dev162578. DOI: 10.1242/dev.162578. PMID: 30333235
    *Co-corresponding author. Featured in a Research Spotlight, Cover Article.  *Co-corresponding author. Cover Article with Science Profile.

  8. Butcher JT
    Sci Transl Med. 2018 May 9;10(440). pii: eaat5850. doi: 10.1126/scitranslmed.aat5850
  9. Jennifer M. Richards, Jennie A.M.R. Kunitake, Heather B. Hunt, Alexa N. Wnorowski, Debra W. Lin, Adele L.Boskeyc, Eve Donnelly, Lara A. Estroff, Jonathan T. Butcher
    Acta Biomaterialia, Volume 71, 15 April 2018, Pages 24-36
  10. Sraeyes Sridhar, Duc H.Pham, Terence W. Gee, Joanna Hua, Jonathan T. Butcher
    Current Opinion in Biomedical Engineering, Volume 5, March 2018, Pages 82-89
  11. Mechanotransduction Mechanisms in Mitral Valve Physiology and Disease Pathogenesis
    Leah A. Pagnozzi and Jonathan T. Butcher
    Front Cardiovasc Med. 2017; 4: 83

  12. Dorota Wojciechowska, Albert Ryszard Liberski, Piotr Wilczek, Jonathan Butcher, Michael Scharfschwerdt, Ziyad Hijazi,  Jarosław Kasprzak,  Philippe Pibarot, Richard Bianco
    QScience Connect 2017, 3, 1
  13. Shaohua Wu; Bin Duan; Xiaohong Qin; Jonathan T. Butcher
    Acta Biomater. 2017 Jul 18
  14. Naturally Engineered Maturation of Cardiomyocytes 
    Scuderi GJ, Butcher J
    Front Cell Dev Biol. 2017 May 5;5:50. doi: 10.3389/fcell.2017.00050. eCollection 2017. Review.

  15. Heart Function and Hemodynamics Analysis for Zebrafish Embryos
    Yalcin HC, Amindari A, Butcher JT, Althani A, Yacoub M.
    Dev Dyn. 2017 Mar 1

  16. Wang Y, Wu B, Farrar E, Lui W, Lu P, Zhang D, Alfieri CM, Mao K, Chu M, Yang D, Xu D, Rauchman M, Taylor V, Conway SJ, Yutzey KE, Butcher JT, Zhou B.
    Eur Heart J. 2017 Mar 1;38(9):675-686.
  17. Developmental mechanisms of aortic valve malformation and disease.
    Wu B, Wang Y, Xiao F, Butcher JT, Yutzey KE, Zhou B. 
    Annu Rev Physiol. 2017 Feb 10;79:21-41

  18. Optimizing Photo-Encapsulation Viability of Heart Valve Cell Types in 3D Printable Composite Hydrogels.
    Kang LH, Armstrong PA, Lee LJ, Duan B, Kang KH, Butcher JT.
    Ann Biomed Eng. 2017 Feb;45(2):360-377

  19. JuPOETs: a constrained multiobjective optimization approach to estimate biochemical model ensembles in the Julia programming language.
    Bassen DM, Vilkhovoy M, Minot M, Butcher JT, Varner JD.
    BMC Syst Biol. 2017 Jan 25;11(1):10. 

  20. Matrix stiffening promotes a tumor vasculature phenotype.
    Bordeleau F, Mason BN, Lollis EM, Mazzola M, Zanotelli MR, Somasegar S, Califano JP, Montague C, LaValley DJ, Huynh J, Mencia-Trinchant N, Negrón Abril YL, Hassane DC, Bonassar LJ, Butcher JT, Weiss RS, Reinhart-King CA.
    Proc Natl Acad Sci U S A. 2016 Dec 29. pii: 201613855. doi: 10.1073/pnas.1613855114. [Epub ahead of print], PMID: 28034921 

  21. Living Nano-Micro Fibrous Woven Fabric/Hydrogel Composite Scaffolds for Heart Valve Engineering
    Shaohua Wu, Bin Duan, Xiaohong Qin, Jonathan T. Butcher
    Acta Biomaterialia, Volume 51, 15 March 2017, Pages 89–100

  22. Population Heterogeneity in the Epithelial to Mesenchymal Transition Is Controlled by NFAT and Phosphorylated Sp1.
    Gould R, Bassen DM, Chakrabarti A, Varner JD, Butcher JT.
    PLoS Comput Biol. 2016 Dec 27;12(12):e1005251. doi: 10.1371/journal.pcbi.1005251. PMID: 28027307 

  23. Valve interstitial cell tensional homeostasis directs calcification and extracellular matrix reModeling processes via RhoA signaling.
    Farrar, EJ; Pramil, V; Richards, JM; Mosher, CZ; Butcher, JT
    BIOMATERIALS, 105 25-37; 10.1016/j.biomaterials.2016.07.034 OCT 2016

  24. Fabrication of Aligned Nanofiber Polymer Yarn Networks for Anisotropic Soft Tissue Scaffolds.
    Wu S, Duan B, Liu P, Zhang C, Qin X, Butcher JT.
    ACS Appl. Mater. Interfaces, 2016, 8 (26), pp 16950–16960. DOI: 10.1021/acsami.6b05199, Publication Date (Web): June 15, 2016 

  25. Cadherin-11 Overexpression Induces Extracellular Matrix Remodeling and Calcification in Mature Aortic Valves.
    Sung DC, Bowen CJ, Vaidya KA, Zhou J, Chapurin N, Recknagel A, Zhou B, Chen J, Kotlikoff M, Butcher JT.
    Arterioscler Thromb Vasc Biol. 2016 Jun 16. pii: ATVBAHA.116.307812. [Epub ahead of print] PMID: 27312222

  26. Duan B, Yin Z, Hockaday Kang L, Magin RL, Butcher JT.
    Acta Biomater. 2016 Mar 3. pii: S1742-7061(16)30091-5. doi: 10.1016/j.actbio.2016.03.007. [Epub ahead of print] PMID: 26947381
  27. JM Richards, I El-Hamamsy, S Chen, Z Sarang, P Sarathchandra, MH Yacoub, AH Chester, and JT Butcher. Am J Path
  28. Quantitative three-dimensional imaging of live avian embryonic morphogenesis via micro-computed tomography
    Henning AL, Jiang MX, Yalcin HC, Butcher JT . Developmental Dynamics
  29. Hemodynamic patterning of the avian atrioventricular valve
    Yalcin HC, Shekhar A, McQuinn TC, Butcher JT. Developmental Dynamics
  30. Transforming growth factor b, bone morphogenetic protein, and vascular endothelial growth factor mediate phenotype maturation and tissue remodeling by embryonic valve progenitor cells: relevance for heart valve tissue engineering 
    Chiu YN, Norris RA, Gretchen M, Recknagel A, Butcher JT. Tissue Engineering 
  31. Two-photon microscopy-guided femtosecond-laser photoablation of avian cardiogenesis: noninvasive creation of localized heart defects
    Yalcin HC, Shekhar A, Nishimura N, Rane AA, Schaffer CB, Butcher JT. Am J Physiol Heart Circ Physiol 
  32. Yalcin HC, Shekhar A, Rane AA, Butcher JT. Journal of Visualized Experiments
  33. Use of ultrasound imaging to map propagating action potential waves in the heart 
    Otani NF, Singh R, Neumann A, Fenton FH, Infanger DW, Butcher JT, Luther S, Gilmour Jr RF. Computing in Cardiology 
  34. Mechanobiology of the aortic valve 
    Butcher JT, Simmons CA, Warnock JN. Journal of Heart Valve Disease 
  35. Neonatal and adult cardiovascular pathophysiological remodeling and repair 
    Norris RA, Borg TK, Butcher JT, Markwald RR. Annals of the New York Academy of Sciences
  36. Metzler SA, Pregonero CA, Butcher JT, Burgess SC, Warnock JN. Journal of Heart Valve Disease
  37. Quantitative volumetric analysis of cardiac morphogenesis assessed through micro-computed tomography 
    Butcher JT, Sedmera D, Guldberg RE, Markwald RR. Developmental Dynamics
  38. Periostin promotes atrioventricular mesenchyme matrix invasion and remodeling mediated by integrin signaling through rho/pi 3-kinase 
    Butcher JT, Norris RA, Hoffman S, Mjaatvedt CH, Markwald RR. Developmental Biology 
  39. Transitions in early embryonic atrioventricular valvular function correspond with changes in cushion biomechanics that are predictable by tissue composition 
    Butcher JT, McQuinn TC, Sedmera D, Turner D, Markwald RR. Circulation Research
  40. The next frontier in cardiovascular developmental biology - an integrated approach to adult disease? 
    Markwald RR, Butcher JT. Nature Clinical Practice - Cardiovascular Medicine
  41. Valvular endothelial cells and the mechanoregulation of valvular pathology 
    Butcher JT, Nerem RM. Philosophical Transactions of the Royal Society B - Biological Sciences
  42. Valvulogenesis: the moving target 
    Butcher JT, Markwald RR. Philophical Transaction of the Royal Society B: Biological Sciences
  43. Equibiaxial strain stimulates fibroblastic phenotype shift in smooth muscle cells in an engineered tissue model of the aortic wall 
    Butcher JT, Barrett BC, Nerem RM. Biomaterials
  44. Valvular endothelial cells regulate the phenotype of interstitial cells in co-culture: effects of steady shear stress
    Butcher JT, Nerem RM. Tissue Engineering
  45. Transcriptional profiles of valvular and vascular endothelial cells reveals phenotypic differences: influence of shear stress
    Butcher JT, Tressel S, Johnson T, Turner D, Sorescu G, Jo H, Nerem RM. Arteriosclerosis, Thrombosis, and Vascular Biology
  46. Unique morphology and focal adhesion development of valvular endothelial cells in static and fluid flow environments
    Butcher JT, Penrod AM, Garcia AJ, Nerem RM. Arteriosclerosis, Thrombosis, and Vascular Biology
  47. Porcine aortic valve interstitial cells in three-dimensional culture: comparison of phenotype with aortic smooth muscle cells 
    Butcher JT, Nerem RM. Journal of Heart Valve Disease

  48. Gould RA, Yalcin HC, MacKay JL, Sauls K, Norris R, Kumar S, Butcher JT.
    Curr Biol. 2016 Jan 11;26(1):27-37. doi: 10.1016/j.cub.2015.11.033. Epub 2015 Dec 24. PMID: 26725196
  49. Levine RA, Hagége AA, Judge DP, Padala M, Dal-Bianco JP, Aikawa E, Beaudoin J, Bischoff J, Bouatia-Naji N, Bruneval P, Butcher JT, Carpentier A, Chaput M, Chester AH, Clusel C, Delling FN, Dietz HC, Dina C, Durst R, Fernandez-Friera L, Handschumacher MD, Jensen MO, Jeunemaitre XP, Le Marec H, Le Tourneau T, Markwald RR, Mérot J, Messas E, Milan DP, Neri T, Norris RA, Peal D, Perrocheau M, Probst V, Pucéat M, Rosenthal N, Solis J, Schott JJ, Schwammenthal E, Slaugenhaupt SA, Song JK, Yacoub MH; Leducq Mitral Transatlantic Network.
    Nat Rev Cardiol. 2015 Dec;12(12):689-710. doi: 10.1038/nrcardio.2015.161. Epub 2015 Oct 20. Review. PMID: 26483167
  50. Lindsey SE, Menon PG, Kowalski WJ, Shekhar A, Yalcin HC, Nishimura N, Schaffer CB, Butcher JT, Pekkan K.
    Biomech Model Mechanobiol. 2015 Aug;14(4):735-51. doi: 10.1007/s10237-014-0633-1. Epub 2014 Nov 23. PMID: 25416845
  51. Bowen CJ, Zhou J, Sung DC, Butcher JT.
    Dev Biol. 2015 Nov 1;407(1):145-57. doi: 10.1016/j.ydbio.2015.07.012. Epub 2015 Jul 16. PMID: 26188246
  52. Cheung DY, Duan B, Butcher JT.
    Expert Opin Biol Ther. 2015;15(8):1155-72. doi: 10.1517/14712598.2015.1051527. Epub 2015 Jun 1. Review. PMID: 26027436
  53. Judge DP, Neamatalla H, Norris RA, Levine RA, Butcher JT, Vignier N, Kang KH, Nguyen Q, Bruneval P, Perier MC, Messas E, Jeunemaitre X, de Vlaming A, Markwald R, Carrier L, Hagège AA.
    J Cardiovasc Dev Dis. 2015;2(2):48-65. Epub 2015 Apr 21. PMID: 26819945
  54. Duan B, Hockaday LA, Das S, Xu C, Butcher JT.
    Tissue Eng Part C Methods. 2015 Aug;21(8):795-807. doi: 10.1089/ten.TEC.2014.0589. Epub 2015 Apr 13. PMID: 25594437
  55. Endothelial-derived oxidative stress drives myofibroblastic activation and calcification of the aortic valve.
    Farrar, E.J.; Huntley, G.D., and Butcher, J.T.
    PLoS One. 2015 Apr 13;10(4):e0123257

  56. Gregg CL, Recknagel AK, Butcher JT.
    Methods Mol Biol. 2015;1189:47-61. doi: 10.1007/978-1-4939-1164-6_4. PMID: 25245686
  57. Frendl CM, Tucker SM, Khan NA, Esch MB, Kanduru S, Cao TM, García AJ, King MR, Butcher JT.
    Biomaterials. 2014 Sep;35(27):7714-23. doi: 10.1016/j.biomaterials.2014.05.075. Epub 2014 Jun 20. PMID: 24952977
  58. 3D printed hydrogel technologies for tissue engineered heart valves.
    Hockaday, L., Duan, B., Kang, K., and Butcher, J. 
    3D Printing and Additive Manufacturing. September 2014, 1(3): 122-136.

  59. Lindsey SE, Butcher JT, Yalcin HC.
    Front Physiol. 2014 Aug 21;5:318. doi: 10.3389/fphys.2014.00318. eCollection 2014. Review. PMID: 25191277 
  60. Mahler GJ, Frendl CM, Cao Q, Butcher JT.
    Biotechnol Bioeng. 2014 Nov;111(11):2326-37. doi: 10.1002/bit.25291. Epub 2014 Aug 5. PMID: 24898772
  61. The influence of external free energy and homeostasis on growth and shape change.
    Buskohl, P., Butcher, J.T., and Jenkins, J. 
    Journal of the Mechanics and Physics of Solids. 64: 338-350. Volume 64

  62. The living aortic valve: from molecules to function.
    Chester, A.H., El-Hamamsy, I., Butcher, J.T.
    Glob. Cardiol. Sci. Pract. 2014 Jan 29;2014(1):52-77

  63. Zhou J, Bowen C, Lu G, Knapp Iii C, Recknagel A, Norris RA, Butcher JT.
    Cells Tissues Organs. 2013;198(4):300-10. doi: 10.1159/000356762. Epub 2013 Dec 20.
  64. Gregg CL, Butcher JT.
    Birth Defects Res C Embryo Today. 2013 Jun;99(2):106-20. doi: 10.1002/bdrc.21034. Review.
  65. Tarsi GM, Gould RA, Chung JA, Xu AZ, Bozkurt A, Butcher JT.
    J Biomech. 2013 Jul 26;46(11):1938-42. doi: 10.1016/j.jbiomech.2013.05.014. Epub 2013 Jun 19.
  66. Duan B, Hockaday LA, Kapetanovic E, Kang KH, Butcher JT.
    Acta Biomater. 2013 Aug;9(8):7640-50. doi: 10.1016/j.actbio.2013.04.050. Epub 2013 May 3.
  67. Kang KH, Hockaday LA, Butcher JT.
    Biofabrication. 2013 Sep;5(3):035001. doi: 10.1088/1758-5082/5/3/035001. Epub 2013 May 2.
  68. Duan B, Kapetanovic E, Hockaday LA, Butcher JT.
    Acta Biomater. 2014 May;10(5):1836-46. doi: 10.1016/j.actbio.2013.12.005.
  69. Gould RA, Aboulmouna LM, Varner JD, Butcher JT.
    Wiley Interdiscip Rev Syst Biol Med. 2013 May-Jun;5(3):289-305. doi: 10.1002/wsbm.1217. Epub 2013 Mar 5. Review.
  70. Valvular endothelial cells inhibit calcification of valvular interstitial cells in mechanically stressed 3D culture.
    Richards, J., Eli-Hamamsy, I., Chen, S., Yacoub, M.H., Chester, A.H., and Butcher. J.T.
    American Journal of Pathology May;182(5):1922-31.

  71. Multidisciplinary inquiry-based learning using an ex-ovo chicken culture platform: Role of vitamin A on embryonic morphogenesis.
    Buskohl, P.R., Gould, R. A., Curran, S., Archer, S., and Butcher, J.T.
    The American Biology Teacher. 2012 Nov/Dec. 74(9): 636-643.

  72. Inflammatory cytokines induce endothelial to mesenchymal transformation in valve endothelial cells via Akt/NFkB.
    Mahler, G.J., Farrar, E., and Butcher, J.T.
    Arteriosclerosis, Thrombosis, and Vascular Biology 2013 Jan;33(1):121-30.

  73. 3D Bioprinting of heterogeneous aortic valve conduits with alginate/gelatin hydrogels
    Duan B, Hockaday LA, Kang KH, Butcher JT. 
    Journal of Biomedical Materials Research, Part A. J Biomed Mater Res A. 2013 May;101(5):1255-64
  74. Multi-scale Biomechanical Remodeling in Aging and Genetic Mutant Murine Mitral Valve Leaflets: Insights into Marfan Syndrome.
    Gould, R., Sinha, R., Aziz, H., Rouf, R., Deitz, H., Judge, D., and Butcher, J.T.
    PLoS One. 2012;7(9):e44639.

  75. Rapid 3D printing of anatomically accurate and mechanically heterogeneous aortic valve hydrogel scaffolds
    Hockaday LA, Kang KH, Colangelo NW, Cheung PY, Duan B, Malone E, Wu J, Girardi LN, Bonassar LJ, Lipson H, Chu CC, Butcher JT.
    Biofabrication. 2012 Sep;4(3):035005
  76. Computational simulation of hemodynamic-driven growth and remodeling of embryonic atrioventricular valves
    Buskohl PR, Jenkins JT, Butcher JT. Biomechanics and Modeling in Mechanobiology
    Biomech Model Mechanobiol. 2012 Nov;11(8):1205-17.
  77. Serotonin potentiates TGFb3 mediated biomechanical remodeling in the avian atrioventricular valve
    Buskohl, P., Sun, M., Thompson, R., and Butcher, J.T.
    PLoS One. 2012;7(8):e42527.

  78. Quantitative in vivo imaging of embryonic development: Opportunities and challenges
    Gregg CL, Butcher JT. (June 2012)
  79. Valvular heart diseases in the developing world: developmental biology takes center stage 
    Farrar EJ, Butcher JT. Journal of Heart Valve Disease
  80. Cyclic strain anisotropy regulates valvular interstitial cell phenotype and tissue remodeling in three-dimensional culture
    Gould RA, Chin K, Santisakultarm TP, Dropkin A, Richards JM, Schaffer CB, Butcher JT. Acta Biomaterialia
  81. Computational fluid dynamics of developing avian outflow tract heart valves
    Bhardwaj KN, Spitz C, Shekhar A, Yalcin HC, Butcher JT. Annals of Biomedical Engineering
    Annals of Biomedical Engineering. 2012 Oct;40(10):2212-27
  82. Interactions between TGFβ1 and cyclic strain in modulation of myofibroblastic differentiation of canine mitral valve interstitial cells in 3D culture
    Waxman AS, Kornreich BG, Gould RA, Moise SN, Butcher JT. Journal of Veterinary Cardiology
  83. Cardiac developmental toxicity
    Mahler GJ, Butcher JT. Birth Defects Research C Embryo Today
  84. The cycle of form and function in cardiac valvulogenesis
    Lindsey SE, Butcher JT. Aswan Heart Center Science and Practice Series. (Dec 2011)
  85. The mechanobiology of mitral valve function, degeneration, and repair
    Richards JM, Farrar EJ, Kornreich BG, Moise NS, Butcher JT. Journal of Veterinary Cardiology
  86. Quantification of embryonic atrioventricular valve biomechanics during morphogenesis
    Buskohl PR, Gould RA, Butcher JT. Journal of Biomechanics
  87. Inflammatory Regulation of Valvular Remodeling: The Good(?), the Bad, and the Ugly
    Mahler GJ, Butcher JT. International Journal of Inflammation
  88. Aortic valve disease and treatment: The need for naturally engineered solutions
    Butcher JT, Mahler GJ, Hockaday LA. Advanced Drug Delivery Review
  89. Gould RA, Butcher JT. Journal of Visualized Experiments (Video Journal)
  90. Isolation and culture of avian embryonic valvular progenitor cells
    Mahler, G.J., and Butcher, J.T. Journal of Visualized Experiments 2010. Dec 29;(46) (Video Journal)

  91. Quantitative three-dimensional analysis of embryonic chick morphogenesis via microcomputed tomography
    Kim JS, Min J, Recknagel AK, Riccio M, Butcher JT. The Anatomical Record
  92. Two-photon guided femtosecond-laser photoablation of avian cardiogenesis: noninvasive creation of localized heart defects
    Yalcin, H., Shekar, A., Rane, A., Nishimura, N., Shaffer, C., and Butcher, J.T.
    American Journal of Physiology – Heart and Circulatory Physiology. Nov; 299(5): H1728-35. 2010. 

  93. Arterial and aortic valve calcification inversely correlates with osteoporotic bone remodeling: a role for inflammation.
    Hjortnaes, J., Butcher, J.T., Figueiredo, J., Riccio, M., Kohler, R., Weissleder, R., and Aikawa, E. 
    European Heart Journal 31, 1975-1984. 2010.

Books and Book Chapters

  1. Bioprinting Cardiovascular Organs.
    Hussain, Y, and Butcher, JT.
    3D Printing: Applications in Cardiovascular Medicine. Edited by SJ Al’Aref, B Mosadegh, S Dunham, JK Min. Academic Press, London. 2018

  2. The role of bone morphogenetic proteins in valvulogenesis.
    Gould, R.A., and Butcher, J.T.
    In Inflammatory Response in Cardiac Surgery. Gabriel and Gabriel Editors. 2013, Springer: New York. ISBN 978-1-4471-4429-8.

  3. Aortic Heart Valve Tissue Regeneration. In: Tissue and Organ Regeneration: Advances in Micro and Nanotechnology.
    Duan B, Hockaday LA, Kang KH, Butcher JT.
    Edited by Zhang LJ, Khademhosseini, A, Webster TJ, Pan Stanford Publishing, Singapore, 2012.

  4. Construction and adaptation of an open source rapid prototyping machine for biomedical research purposes - a multinational collaborative development 
    Lixandrao Filho, A.L., Noritomi, P.Y., da Silva, J.V., Inforcatti Neto, P., Cheung, P.Y., Colangelo, N., Kang, H., Butcher, J.T., and E. Malone.
    in Innovative Developments in Design and Manufacturing, P.J. Bartolo, Editor. 2009, CRC Press: Boca Raton, FL.

Invited Presentations

  1. Mechanoregulation of heart valve morphogenesis
    Invited Keynote. 2018 World Congress of Biomechanics. Dublin Ireland. July 11, 2018.

  2. Stem cells in heart valve pathogenesis and regeneration.
    7th Cornell Stem Cell Symposium. May 24, 2018. 

  3. Is there an appropriate in vitro model of aortic valve calcification?
    Heart Valve Society 2018 Annual Meeting. Invited Keynote. New York, NY. April 12, 2018.

  4. Cardiovascular developmental bioengineering.
    Medtronic Inc. Irvine CA. March 20, 2018. 

  5. Notch-NFkB interactions in aortic valve homeostasis and disease.
    Cornell Center for Vertebrate Genomics. Cornell University, Ithaca NY. February 13, 2018.

  6. Aortic valve homeostasis disease, and regeneration.
    Clemson University. Hunter Endowed Lecture. December 7, 2017. Clemson SC. 

  7. Notch Signaling in Aortic Valve Morphogenesis and Homeostasis.
    American Heart Association 2017 Scientific Sessions. November 13, 2017. Los Angeles, CA.

  8. Developmental Reactivation of Cells in Heart Valve Disease Cellular Control of (Re)generation.
    University of Rochester. November 8, 2017. Rochester NY.

  9. The Natural Engineering of Heart Valves: From Stem Cells to Biomaterials.
    Keynote Presentation. Qatar University, Tissue Engineering and Stem Cell Technologies Workshop. Doha, Qatar. October 25, 2017. 

  10. The Mechanobiology of mitral valve development and maturation.
    University of California, Los Angeles. April 24, 2017. Los Angeles, CA.

  11. 3D Printing for Clinical Cardiovascular Applications.
    SelectBIO Conference. March 17, 2017. Boston MA.

  12. Endothelial-Interstitial Cell Communication.
    Invited Keynote. Heart Valve Society 2017 Annual Meeting. March 3, 2017. Monaco.

  13. 3D culture systems for elucidation of mechanobiological mechanisms of valve calcification.
    Invited Keynote. Heart Valve Society 2017 Annual Meeting. March 3, 2017. Monaco. 

  14. The perfect semilunar valve: An Engineer’s Perspective.
    Invited Keynote. Heart Valve Society 2017 Annual Meeting. March 2, 2017. Monaco.

  15. 3D Printing and Biofabrication of Cardiac Valves-Current State and Future Perspectives.
    American Heart Association, 2016 Scientific Sessions. November 14, 2016. New Orleans, LA.

  16. The Mechanobiological Control of Mitral Valve Development, Homeostasis, and Disease Pathogenesis.
    International Cardiology Veterinary Symposium. October 21-23, 2106. Dubrovnik Croatia.

  17. The Mechanobiology of Mitral Valve Morphogenesis.
    Cincinnati Children’s Hospital, Bridging the Outcome from TERM. August 29-30, 2016. 

  18. Hemodynamic regulation of outflow tract and great vessel formation.
    6th International Conference on Engineering Frontiers in Pediatric and Congenital Heart Diseases. Orlando FL. June 10, 2016.

  19. 3D Biofabrication of Complex Living Cardiovascular Tissues.
    Oregon Health Science Center. May 13, 2016.

  20. The Mechanobiology of Heart Valve Development and Maturation.
    Stanford University. May 12, 2016

  21. Endothelial-mesenchymal transformation in aortic valve maturation and postnatal valve remodeling.
    Heart Valve Society 2016 Annual Meeting. New York City, NY. March 18, 2016. 

  22. The Mechanobiology of Aortic Valve Disease and Regeneration.
    University of California, Irvine. Irvine, CA. February 27, 2016.

  23. Biofabrication of complex living cardiovascular tissues.
    Seattle Children’s Hospital, Seattle, WA, November 17, 2015. 

  24. Matrix control of aortic valve interstitial cell phenotype.
    American Heart Association, Scientific Sessions. Orlando, FL, November 10, 2015.

  25. Endothelial Mechanisms of Aortic Valve Biology and Disease.
    Heart Valve Society Inaugural Meeting. Monaco, May 7, 2015.

  26. Mechanical regulation of FilGAP coordinates Rac1 mediated remodeling of the fetal aortic valves.
    Center for Vertebrate Genomics, Cornell University. December 9, 2014. 

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