Mechanotransduction Mechanisms in Mitral Valve Physiology and Disease Pathogenesis
Leah A. Pagnozzi and Jonathan T. Butcher
Front Cardiovasc Med. 2017; 4: 83
Developmental mechanisms of aortic valve malformation and disease.
Wu B, Wang Y, Xiao F, Butcher JT, Yutzey KE, Zhou B.
Annu Rev Physiol. 2017 Feb 10;79:21-41
Award Winner in the Young Investigator Category, 2017 Society for Biomaterials Annual Meeting and Exposition, Minneapolis, MN, April 0508, 2017: Lymph node stiffness-mimicking hydrogels regulate human B-cell lymphoma growth and cell surface receptor expression in a molecular subtype-specific manner
Apoorva, FNU; Tian, YF; Pierpont, TM; Bassen, DM; Cerchietti, L; Butcher, JT; Weiss, RS; Singh, A
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 105 (7):1833-1844; 10.1002/jbm.a.36031 JUL 2017
Matrix stiffening promotes a tumor vasculature phenotype.
Bordeleau F, Mason BN, Lollis EM, Mazzola M, Zanotelli MR, Somasegar S, Califano JP, Montague C, LaValley DJ, Huynh J, Mencia-Trinchant N, Negrón Abril YL, Hassane DC, Bonassar LJ, Butcher JT, Weiss RS, Reinhart-King CA.
Proc Natl Acad Sci U S A. 2016 Dec 29. pii: 201613855. doi: 10.1073/pnas.1613855114. [Epub ahead of print], PMID: 28034921
Valve interstitial cell tensional homeostasis directs calcification and extracellular matrix reModeling processes via RhoA signaling.
Farrar, EJ; Pramil, V; Richards, JM; Mosher, CZ; Butcher, JT
BIOMATERIALS, 105 25-37; 10.1016/j.biomaterials.2016.07.034 OCT 2016
Cadherin-11 Overexpression Induces Extracellular Matrix Remodeling and Calcification in Mature Aortic Valves.
Sung DC, Bowen CJ, Vaidya KA, Zhou J, Chapurin N, Recknagel A, Zhou B, Chen J, Kotlikoff M, Butcher JT.
Arterioscler Thromb Vasc Biol. 2016 Jun 16. pii: ATVBAHA.116.307812. [Epub ahead of print] PMID: 27312222
