Developmental Redux of Adult Valve Disease

Jennifer M. Richards, Jennie A.M.R. Kunitake, Heather B. Hunt, Alexa N. Wnorowski, Debra W. Lin, Adele L.Boskeyc, Eve Donnelly, Lara A. Estroff, Jonathan T. Butcher
Acta Biomaterialia, Volume 71, 15 April 2018, Pages 24-36
Sraeyes Sridhar, Duc H.Pham, Terence W. Gee, Joanna Hua, Jonathan T. Butcher
Current Opinion in Biomedical Engineering, Volume 5, March 2018, Pages 82-89

Mechanotransduction Mechanisms in Mitral Valve Physiology and Disease Pathogenesis
Leah A. Pagnozzi and Jonathan T. Butcher
Front Cardiovasc Med. 2017; 4: 83

Developmental mechanisms of aortic valve malformation and disease.
Wu B, Wang Y, Xiao F, Butcher JT, Yutzey KE, Zhou B. 
Annu Rev Physiol. 2017 Feb 10;79:21-41

Matrix stiffening promotes a tumor vasculature phenotype.
Bordeleau F, Mason BN, Lollis EM, Mazzola M, Zanotelli MR, Somasegar S, Califano JP, Montague C, LaValley DJ, Huynh J, Mencia-Trinchant N, Negrón Abril YL, Hassane DC, Bonassar LJ, Butcher JT, Weiss RS, Reinhart-King CA.
Proc Natl Acad Sci U S A. 2016 Dec 29. pii: 201613855. doi: 10.1073/pnas.1613855114. [Epub ahead of print], PMID: 28034921 

Valve interstitial cell tensional homeostasis directs calcification and extracellular matrix reModeling processes via RhoA signaling.
Farrar, EJ; Pramil, V; Richards, JM; Mosher, CZ; Butcher, JT
BIOMATERIALS, 105 25-37; 10.1016/j.biomaterials.2016.07.034 OCT 2016

Cadherin-11 Overexpression Induces Extracellular Matrix Remodeling and Calcification in Mature Aortic Valves.
Sung DC, Bowen CJ, Vaidya KA, Zhou J, Chapurin N, Recknagel A, Zhou B, Chen J, Kotlikoff M, Butcher JT.
Arterioscler Thromb Vasc Biol. 2016 Jun 16. pii: ATVBAHA.116.307812. [Epub ahead of print] PMID: 27312222

JM Richards, I El-Hamamsy, S Chen, Z Sarang, P Sarathchandra, MH Yacoub, AH Chester, and JT Butcher. Am J Path
Mechanobiology of the aortic valve 
Butcher JT, Simmons CA, Warnock JN. Journal of Heart Valve Disease 

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